In collaboration with Prof A. Hoffman of the Hebrew University School of Pharmacy, we conducted a study examining the bioequivalence of oral administration vs oral spray of a cannabinoid combination. This trial in healthy human subjects was a PK-PD study using QST, cold pressure tests, and computerized task performance rapidity tests. We have analyzed the PK data and are now analyzing the pharmacodynamics data. Based on our preliminary analysis, we are cautiously optimistic that we may be able to show benefit from a new form of cannabis administration compared with existing protocols.